In orthopedics, Non-Union refers to a fracture that fails to heal within the expected time frame, typically around 6–9 months, despite adequate treatment. This occurs when the broken bone lacks the biological or mechanical conditions necessary for proper healing. Causes may include poor blood supply, infection, excessive movement at the fracture site, or underlying medical conditions. Treatment options include bone grafting, internal or external fixation, and biologic stimulators like bone growth factors to promote healing.